TernaryTx news.
Ternary-led hackathon brings AI and drug discovery specialists together to build the next generation of scientific tools
- The three-day ‘Building an AI Scientist’ hackathon brought together engineers, scientists, founders and AI specialists to develop practical tools addressing some of drug discovery’s most difficult challenges.
- The event culminated in Apoptosis AI taking the top prize for its work on a decision-support platform designed to help pharmaceutical teams assess potential drug targets more quickly and confidently.
TernaryTx raises €4.1 million in seed funding
Daphni leads the €4.1 million round, co-invested by Pace Ventures, i&i Biotech Fund and UK Innovation & Science Seed Fund (managed by Future Planet Capital).
This investment enables us to scale our AI-driven platform to discover molecular glue therapeutics. By combining physics-informed AI with rapid experimental validation, TernaryTx is turning what has historically been a chance discovery process into a repeatable engineering system for drug discovery.
As part of its next phase, Dr Ian Taylor was appointed to the Board. Dr Taylor is a veteran of targeted protein degradation research and was recently CSO and President of R&D at Arvinas.
From puzzle pieces to predictions: Holly on interning with TernaryTx’s tech team
Holly, a PhD student at the University of Warwick, spent her internship working out whether two proteins will interact, and how good teamwork, communication and planning can get an enormous amount done in a short space of time.
Read the full story →Preprint: benchmarking FEP against Boltz-2 for binding affinity prediction
This study presents the first comprehensive comparison of two computational methods for predicting binding affinity: the accurate-but-costly Free Energy Perturbation (FEP) and the fast co-folding model Boltz-2. Across 140 measurements on six complexes, FEP consistently demonstrated strong predictive accuracy. The paper also shows the ability of FEP to predict selectivity between off-targets.
Read preprint →TernaryTx comes out of stealth
Platform announced: Leopard, Puffin, Gecko, and Octopus — four interconnected tools combining AI and molecular dynamics for the rational design of molecular glue therapeutics targeting undruggable proteins.